The effect of orlistat-induced weight loss on interleukin-6 and C-reactive protein levels in obese subjects

Yesilbursa D., Serdar A., Heper Y., Sarac M., Coskun S., Kazazoglu A., ...More

ACTA CARDIOLOGICA, vol.60, no.3, pp.265-269, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 3
  • Publication Date: 2005
  • Doi Number: 10.2143/ac.60.3.2005002
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.265-269
  • Bursa Uludag University Affiliated: No


Objective - Inflammation plays a major role in the pathogenesis of atherosclerosis. Obesity is an independent risk factor for cardiovascular disease, which may be mediated by increased secretion of proinflammatory cytokines by adipose tissue. The aim of this study is to investigate changes in the inflammatory markers interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) during weight reduction with orlistat treatment in obese patients.