This study aims classification of phosphorus magnetic resonance spectroscopic imaging (P-31-MRSI) data of human brain tumors using machine-learning algorithms. The metabolite peak intensities and ratios were estimated for brain tumor and healthy P-31 MR spectra acquired at 3T. The spectra were classified based on metabolite characteristics using logistic regression and support vector machine. This study showed that machine learning could be successfully applied for classification of P-31-MR spectra of brain tumors. Future studies will measure the performance of classification algorithms for P-31-MRSI of brain tumors in a larger patient cohort.