Immunohistochemical expression of human epidermal growth factor receptor (HER)-4 and prognosis in patients with metastatic breast cancer
JOURNAL OF BUON, vol.21, no.3, pp.564-569, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 21 Issue: 3
- Publication Date: 2016
- Journal Name: JOURNAL OF BUON
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.564-569
- Bursa Uludag University Affiliated: Yes
Abstract
Purpose: The clinical value of HER4 - a cell surface receptor that belongs to the human epidermal growth factor receptor family - for predicting survival outcomes in patients with breast cancer remains controversial. Herein, we sought to investigate the prognostic significance of HER4 immunohistochemical expression with respect to progression-free survival (PFS) and overall survival (OS) in Turkish patients with metastatic breast cancer (MBC).