Analysis of apoptotic, platelet-derived, endothelial-derived, and tissue factor-positive microparticles of children with acute lymphoblastic leukemia during induction therapy


Yenigurbuz F. D., Kizmazoglu D., Ates H., Erdem M., Tufekci O., Yilmaz S., ...Daha Fazla

BLOOD COAGULATION & FIBRINOLYSIS, cilt.30, sa.4, ss.149-155, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1097/mbc.0000000000000811
  • Dergi Adı: BLOOD COAGULATION & FIBRINOLYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.149-155
  • Anahtar Kelimeler: acute lymphoblastic leukemia, childhood, microparticles, thromboembolism, CIRCULATING MICROPARTICLES, THROMBOSIS, CANCER, PREVALENCE, ACTIVATION, DISEASE, EVENTS, CELLS
  • Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Objectives Thromboembolism is one of the most common complications during induction therapy of pediatric acute lymphoblastic leukemia (ALL). Procoagulant microparticles in the circulation may cause thromboembolic events. The aim of our study was to determine the levels of apoptotic, platelet-derived, endothelial-derived, and tissue factor-positive microparticles of children with ALL at diagnosis and during induction therapy.