Topological analysis of HIV/AIDS drugs using graph theory, linear regression models, and data science approaches

Prakasha, K.N.; Dixit, Arun; Ayna, HACER; YURTTAŞ GÜNEŞ, AYSUN; CANGÜL, İSMAİL; Paul, Kiran

doi:10.1201/9781003650201-86

Topological analysis of HIV/AIDS drugs using graph theory, linear regression models, and data science approaches

Prakasha K., Dixit A. C., Ayna H. O., YURTTAŞ GÜNEŞ A., CANGÜL İ. N., Paul K. P.

in: Information and Communication Systems, CRC Press, pp.523-527, 2026

Publication Type: Book Chapter / Chapter Research Book
Publication Date: 2026
Doi Number: 10.1201/9781003650201-86
Publisher: CRC Press
Page Numbers: pp.523-527
Keywords: Lodeg indices, QSPR analysis, Randic type-Hadi, Regression model, SDI
Bursa Uludag University Affiliated: Yes

Abstract

In this paper, we discuss Randic type- Hadi, SDI, Lodeg indices of the chemical structures of Lamivudine, Tipranavir, Lopinavir, Elvitegravir which are widely used for the treatment of HIV/AIDS. We analyze these indices in relation to critical properties such as melting point (MP), Flashing point (FP), Enthalpy.