The demographic datas of chronic granulomatous disease patients and the comparation of the clinical datas before and after interferon-gamma treatment in our country

Filiz, Serkan; KOCACIK UYGUN, DİLARA; Sanal, Ozden; Camcioglu, Yildiz; SOMER, Ayper; Barlan, Isil; KILIÇ GÜLTEKİN, SARA; Reisli, Ismail; Patiroglu, Turkan; Yildiran, Alisan; Artac, Hasibe; Metin, Ayse; Aksu, Guzide; Genel, Ferah; Ozturk, Can; Celmeli, Fatih; Bingol, Aysen; Yegin, Olcay

The demographic datas of chronic granulomatous disease patients and the comparation of the clinical datas before and after interferon-gamma treatment in our country

Filiz S., KOCACIK UYGUN D. F., Sanal O., Camcioglu Y., SOMER A., Barlan I., ...Daha Fazla

ASTIM ALLERJI IMMUNOLOJI, cilt.11, sa.3, ss.153-161, 2013 (ESCI, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 11 Sayı: 3
Basım Tarihi: 2013
Dergi Adı: ASTIM ALLERJI IMMUNOLOJI
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.153-161
Anahtar Kelimeler: Immunologic diseases, interferon-gamma
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objective: Chronic granulomatous disease (CGD) is a genetically heterogeneous primary immunodeficiency that is characterised by bacteria and fungal infections with defective phagocytosis. Interferon-gamma (INF-gamma) has diverse roles in the innate and adaptive responses. Despite several decades of work on INF-gamma treatment in CGD, contraversy remains about its use.