Akademik Veri Yönetim Sistemi
EAOM 2018 Oral Medicine Conference, Gothenburg, İsveç, 27 - 29 Eylül 2018, cilt.48, sa.1, ss.59-60, (Özet Bildiri)
Introduction: Despite the improvement in therapies for cancer, the 5-year survival rates of oral squamous cell carcinoma (OSCC) has not changed significantly in the last 20 years. This fact raises the importance of detection of oral premalignant lesions and oral epithelial dysplasia (OED).
Objectives: We aimed to understand the character of OED in terms of severity, age, sex, location and related tumor development.
Material and Methods: In this retrospective cross-sectional study, proven OED with histopathology between years 2006-2016 in İstanbul University, İstanbul Medical Faculty Pathology Department were reviewed. Statistical data were evaluated with IBM 21.0 program and statistical significance was taken as P < 0.05. Results: A total of 384 biopsies from 275 patients (144 female, 131 male) with the mean age of 59.32 (14-91) were reviewed. The most common type of dysplasia was mild dysplasia (67.8%) and the most common locations were the tongue (40.6%), buccal mucosa (31%) and palatinal mucosa (8.1%) respectively. Buccal mucosa and tongue showed a statistically significant difference according to dysplasia grades P < 0.01 and P < 0.05 respectively. Previous OSCC at the same location was positive in 17(6.1%) of the cases.
Conclusions: Intraoral examination of middle-aged population has an extreme importance in terms of detection of early stage oral cancer and OED. Follow-up of the OSCC cases also needs a careful watch of the oral mucosa and biopsy of the suspicious sites.