Reactivity of benzylic acylammonium chlorides. A novel method for the synthesis of N-phenacylamides.

Coskun N., Tirli F.

SYNTHETIC COMMUNICATIONS, vol.27, no.1, pp.1-9, 1997 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 1
  • Publication Date: 1997
  • Doi Number: 10.1080/00397919708004799
  • Journal Name: SYNTHETIC COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1-9
  • Bursa Uludag University Affiliated: Yes

Abstract

Tertian amines 1 reacted with acid chlorides 2 to give corresponding benzyl chlorides and N-phenacylamides 4. Counterion in species 3 attacked preferentially the benzylic methylene. Effect of substituents in the benzyl group on the reactivity. of acylammonium chlorides 3 was investigated.