Development of Silver-Based Bactericidal Composite Nanofibers by Airbrushing


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Bhullar S., Rana D., Ozsel B. K. , Orhan M. , Jun M. B. G. , Buttar H. S. , ...More

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, vol.18, pp.2951-2955, 2018 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 18
  • Publication Date: 2018
  • Doi Number: 10.1166/jnn.2018.14376
  • Title of Journal : JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
  • Page Numbers: pp.2951-2955

Abstract

In this article, we report a simple, cost-effective and eco-friendly method of airbrushing for the fabrication of antibacterial composite nanofibers using Nylon-6 and silver chloride (AgCl). The Nylon-6 is a widely used polymer for various biomedical applications because of its excellent biocompatibility and mechanical properties. Similarly, silver has also been known for their antibacterial, antifungal, antiviral, and anti-inflammatory properties. In order to enhance the antibacterial functionality of the Nylon-6, composite nanofibers in combination with AgCl have been fabricated using airbrush method. The chemical functional groups and morphological studies of the airbrushed Nylon-6/AgCl composite nanofibers were carried out by FTIR and SEM, respectively. The antibacterial activity of airbrushed Nylon-6/AgCl composite nanofibers was evaluated using Gram + ve (Staphylococcus aureus) and Gram -ve (Escherichia coli) bacterial strains. The results showed that the airbrushed Nylon-6/AgCl composite nanofibers have better antibacterial activity against the tested bacterial strains than the airbrushed Nylon-6 nanofibers. Therefore, the airbrushed Nylon-6/AgCl composite nanofibers could be used as a potential antibacterial scaffolding system for tissue engineering and regenerative medicine.