Filters are used to decontaminate the particles from the outside environment entering different subsystems of vehicles. Conventional air filters can cause a significant pressure drop in the intake air system because of their porous structure. In this study, a cyclone separator was designed and manufactured for the air intake system of an automobile. The pressure drop and the performance parameters of the engine were measured by using a conventional air filter or a cyclone separator in the air intake system. Futhermore, a computational fluid dynamics analysis of the cyclone separator was performed, and the results were compared with the experimental data.