Adrenocortical carcinoma: Single center experience

Sisman P., ŞAHİN A. B., Peynirci H., CANDER S., ÖZ GÜL Ö., ERTÜRK E., ...More

TURKISH JOURNAL OF UROLOGY, vol.40, no.4, pp.462-469, 2017 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.5152/tud.2017.81598
  • Journal Name: TURKISH JOURNAL OF UROLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.462-469
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: Adrenocortical carcinoma is an aggressive endocrine malignancy with an annual incidence of 0.5-2 cases per million. The most important factors that determine prognosis are tumor stage at the time of diagnosis and the success of surgery. However, advanced age, large tumor size, hormone secretion, high Ki-67 index (>10%), tumor necrosis and high mitotic activity are other factors associated with poor prognosis. In the present study, we aimed to evaluate the contribution of the patient and treatment-related factors to the prognosis in adrenocortical carcinoma.