Akademik Veri Yönetim Sistemi
Cardiovascular Academy Digital Congress, İzmir, Türkiye, 16 - 20 Eylül 2020, ss.107
Objective: In most healthy individuals, blood pressure shows a circadian rhythm. Being nondipper in normotensive individuals as well as hypertensives increases the cardiovascular risk. In this study, the relationship between inflammation markers and nondipper pattern in normotensive individuals was investigated. Method: Patients with office blood pressure measurements <140/90 mmHg but suspected of hypertension in differential diagnosis and because of that followed up with ambulatory blood pressure monitoring (ABPM) at our outpatient clinic were retrospectively screened. Based on ABPM results, hypertensive patients were excluded. Remained normotensive individuals were included in the study and divided into 2 groups as dippers and nondippers according to decline in nighttime systolic blood pressure. Monocyte / high density lipoprotein ratio (MHR), platelet/ lymphocyte ratio (PLR) and neutrophil / lymphocyte ratio (NLR) as inflammation markers were derived from biochemical laboratory tests and complete blood count findings. Then, these markers were evaluated with respect to dipping status. Results: A total of 131 patients (mean age: 49.2 ± 15.1 years, 76% females) were included in the study. Among these, 55 (42%) patients were grouped as dippers, 76 (58%) patients were grouped as non dippers. None of MHR (p=0.929), NLR (p=0.152) and PLR (p= 0.110) significantly differed between the groups Conclusion: MHR, PLR and NLR were not predictors of non dipping in normotensive individuals