Soluble forms of extracellular cytokeratin 18 may differentiate simple steatosis from nonalcoholic steatohepatitis


Yilmaz Y., Dolar E. , Ulukaya E., Akgoz S., Keskin M., Kiyici M., ...More

WORLD JOURNAL OF GASTROENTEROLOGY, vol.13, no.6, pp.837-844, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.3748/wjg.v13.i6.837
  • Title of Journal : WORLD JOURNAL OF GASTROENTEROLOGY
  • Page Numbers: pp.837-844
  • Keywords: steatosis, steatohepatitis, cytokeratin 18, M30-antigen, M65-antigen, FATTY LIVER-DISEASE, NATURAL-HISTORY, CELL-DEATH, HEPATOCYTE APOPTOSIS, VARIABILITY, FEATURES, BIOPSY, SERA

Abstract

AIM: To investigate whether serum levels of two soluble forms of extracellular cytokeratin 18 (M30-antigen and M65-antigen) may differentiate nonalcoholic steatohepatitis (NASH) from simple steatosis in patients with nonalcoholic fatty liver disease (NAFLD).