Soluble forms of extracellular cytokeratin 18 may differentiate simple steatosis from nonalcoholic steatohepatitis

Yilmaz, Yusuf; Dolar, MAHMUT; Ulukaya, Engin; Akgoz, Semra; Keskin, Murat; Kiyici, Murat; Aker, Sibel; Yilmaztepe, ARZU; Gurel, SELİM; Gulten, Macit; Nak, Selim

doi:10.3748/wjg.v13.i6.837

Soluble forms of extracellular cytokeratin 18 may differentiate simple steatosis from nonalcoholic steatohepatitis

Yilmaz Y., Dolar E., Ulukaya E., Akgoz S., Keskin M., Kiyici M., ...Daha Fazla

WORLD JOURNAL OF GASTROENTEROLOGY, cilt.13, sa.6, ss.837-844, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 13 Sayı: 6
Basım Tarihi: 2007
Doi Numarası: 10.3748/wjg.v13.i6.837
Dergi Adı: WORLD JOURNAL OF GASTROENTEROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.837-844
Anahtar Kelimeler: steatosis, steatohepatitis, cytokeratin 18, M30-antigen, M65-antigen, FATTY LIVER-DISEASE, NATURAL-HISTORY, CELL-DEATH, HEPATOCYTE APOPTOSIS, VARIABILITY, FEATURES, BIOPSY, SERA
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

AIM: To investigate whether serum levels of two soluble forms of extracellular cytokeratin 18 (M30-antigen and M65-antigen) may differentiate nonalcoholic steatohepatitis (NASH) from simple steatosis in patients with nonalcoholic fatty liver disease (NAFLD).