Hypocomplementemic urticarial vasculitis: a rare presentation of systemic lupus erythematosus

Aydogan K., Karadogan S. K. , Adim S. B. , Tunali S.

INTERNATIONAL JOURNAL OF DERMATOLOGY, vol.45, no.9, pp.1057-1061, 2006 (SCI-Expanded) identifier identifier identifier


Background Urticarial vasculitis is a small-vessel vasculitis, presenting clinically as persistent urticarial skin lesions and microscopically as leucocytoclastic vasculitis. Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a distinct type of urticarial vasculitis with multiorgan involvement, whose etiology and link with other diseases are still unknown. Some authors have suggested that HUVS can be accompanied by systemic lupus erythematosus (SLE), and others believe that it is a rare subtype of SLE. Urticarial vasculitis is seen in 7-8% of SLE, while 50% of HUVS patients are diagnosed with SLE.