PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, vol.35, no.5, pp.1284-1290, 2011 (SCI-Expanded)
Article / Article
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Antioxidants, Major depressive disorder, Malondialdehyde, Oxidative stress, CORONARY-ARTERY-DISEASE, LOW-DENSITY-LIPOPROTEIN, SUPEROXIDE-DISMUTASE, LIPID-PEROXIDATION, ANTIOXIDANT STATUS, NITRIC-OXIDE, OXIDIZED LDL, RAT-BRAIN, STRESS, PLASMA
Bursa Uludag University Affiliated:
Purpose: Major depressive disorder (MDD) is a devastating disease that afflicts large populations and has also been accepted to be an independent risk factor for cardiovascular disease (CVD). Oxidative stress seems to play an essential role in the relationship of MOD and CVD. We aimed to determine the level of oxidative stress in patients with MOD and to investigate the effects of long-term antidepressant (AD) treatment on the oxidative-antioxidative system parameters and CVD risk factors.