Discontinuation of RAAS Inhibition in Children with Advanced CKD

van den Belt, Sophie; Heerspink, Hiddo; Kirchner, Marietta; Gracchi, Valentina; Thurn-Valsassina, Daniela; KARABAY BAYAZIT, AYSUN; Niemirska, Anna; Canpolat, Nur; KAPLAN BULUT, İPEK; Azukaitis, Karolis; DÜZOVA, ALİ; Bacchetta, Justine; Shroff, Rukshana; Paripovic, Dusan; ÖZÇAKAR, ZEYNEP; Fidan, Kibriya; ERDOĞAN, HAKAN; Gellermann, Jutta; Wuehl, Elke; de Zeeuw, Dick; Melk, Anette; Querfeld, Uwe; Schaefer, Franz

doi:10.2215/cjn.09750819

Discontinuation of RAAS Inhibition in Children with Advanced CKD

van den Belt S. M., Heerspink H. J. L., Kirchner M., Gracchi V., Thurn-Valsassina D., KARABAY BAYAZIT A., ...Daha Fazla

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, cilt.15, sa.5, ss.625-632, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 15 Sayı: 5
Basım Tarihi: 2020
Doi Numarası: 10.2215/cjn.09750819
Dergi Adı: CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
Sayfa Sayıları: ss.625-632
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background and objectives Although renin-angiotensin-aldosterone system inhibition (RAASi) is a cornerstone in the treatment of children with CKD, it is sometimes discontinued when kidney function declines. We studied the reasons of RAASi discontinuation and associations between RAASi discontinuation and important risk markers of CKD progression and on eGFR decline in the Cardiovascular Comorbidity in Children with CKD study.