Pharmacologic Overview of Chlorogenic Acid and its Metabolites in Chronic Pain and Inflammation

Bagdas D., Gul Z., Meade J. A., Cam B., ÇİNKILIÇ N., GÜRÜN M. S.

CURRENT NEUROPHARMACOLOGY, cilt.18, sa.3, ss.216-228, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 18 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1570159x17666191021111809
  • Dergi Adı: CURRENT NEUROPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE, Psycinfo
  • Sayfa Sayıları: ss.216-228
  • Anahtar Kelimeler: Chlorogenic acid, inflammation, pain, inflammatory, neuropathic, antihyperalgesic, antiallodynic, NF-KAPPA-B, GATED POTASSIUM CHANNELS, GABA RECEPTOR AGONISTS, NITRIC-OXIDE SYNTHASE, INDUCED LIVER-INJURY, OXYGEN SPECIES ROS, HYPERICUM-PERFORATUM, NEUROPATHIC PAIN, CAFFEIC ACID, IN-VITRO
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background: Natural phenolic compounds in medicinal herbs and dietary plants are antioxidants which play therapeutic or preventive roles in different pathological situations, such as oxidative stress and inflammation. One of the most studied phenolic compounds in the last decade is chlorogenic acid (CGA), which is a potent antioxidant found in certain foods and drinks.