Copy For Citation
Samandram R., Çetin Korukçu M., Coşkun N.
SYNTHETIC COMMUNICATIONS, vol.51, pp.2349-2356, 2021 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
51
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Publication Date:
2021
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Doi Number:
10.1080/00397911.2021.1934876
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Journal Name:
SYNTHETIC COMMUNICATIONS
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, Chimica, EMBASE
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Page Numbers:
pp.2349-2356
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Keywords:
1, 2-dihydroquinazoline-3-oxide, H2O2 oxidation, N-oxides, quinazoline, quinazoline-3-oxide, RING-CHAIN TAUTOMERISM, PHOTOCHEMISTRY, QUINOLINE
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Bursa Uludag University Affiliated:
Yes
Abstract
2-Aminobenzaldehyde, 1-(2-aminophenyl)ethanone, and 2-aminophenyl phenyl methanone oximes 1 were reacted with aromatic aldehydes to give the corresponding 1,2-dihydroquinazoline-3-oxides 2. The latter were converted in high yields to a series of quinazoline-3-oxides 3 using an environmentally benign H2O2-tungstate oxidant system at room temperature. A high yielding one-pot procedure was also developed for the synthesis of compounds 3.