Synthesis, Structural Analysis and Antimicrobial Activities of Novel Water Soluble Ionic Liquids Derived from N-Heterocyclic Carbene Salts

Kunduracioglu A., Gube O., Hames-Kocabas E. E., Eyupoglu V., Sonmez F.

CROATICA CHEMICA ACTA, vol.89, no.1, pp.105-110, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 89 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.5562/cca2599
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.105-110
  • Keywords: ionic liquids, N-heterocyclic carbenes, antimicrobial activity, N-functional substituents, BIOLOGICAL EVALUATION, COMPLEXES, NANOPARTICLES, STABILIZATION, CATALYSIS, BIOFILM, AGENTS
  • Bursa Uludag University Affiliated: No


Six N-heterocyclic Carbene based Ionic Liquids (ILs) have been synthesized by conventional methods. The ILs were spectroscopically characterized by NMR and FT-IR techniques. Their in vitro antimicrobial activities were determined towards gram-positive and gram-negative bacterias and yeast strains using minimum inhibition concentration (MIC) assay. The best inhibition performances were obtained with compound 1 due to its more hydrophilic nature compared with the others. It exhibited 1 mg L-1 MIC value against to the most bacteria while the others showed 4 mg L-1.