Synthesis, Structural Analysis and Antimicrobial Activities of Novel Water Soluble Ionic Liquids Derived from N-Heterocyclic Carbene Salts

Kunduracioglu A., Gube O., Hames-Kocabas E. E., Eyupoglu V., Sonmez F.

CROATICA CHEMICA ACTA, cilt.89, sa.1, ss.105-110, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 89 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5562/cca2599
  • Dergi Adı: CROATICA CHEMICA ACTA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.105-110
  • Anahtar Kelimeler: ionic liquids, N-heterocyclic carbenes, antimicrobial activity, N-functional substituents, BIOLOGICAL EVALUATION, COMPLEXES, NANOPARTICLES, STABILIZATION, CATALYSIS, BIOFILM, AGENTS
  • Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Six N-heterocyclic Carbene based Ionic Liquids (ILs) have been synthesized by conventional methods. The ILs were spectroscopically characterized by NMR and FT-IR techniques. Their in vitro antimicrobial activities were determined towards gram-positive and gram-negative bacterias and yeast strains using minimum inhibition concentration (MIC) assay. The best inhibition performances were obtained with compound 1 due to its more hydrophilic nature compared with the others. It exhibited 1 mg L-1 MIC value against to the most bacteria while the others showed 4 mg L-1.