Comparison of human and bovine tuberculin results in children vaccinated with BCG at three months of age UCUNCU AYDA BCG ASISI YAPILAN BEBEKLERDE HUMAN TUBERKULIN VE BOVIN TUBERKULIN YANITLARININ KARSILASTIRILMASI


Gursucu S., Koksal N., Sapan N., Ildirim I.

Cocuk Sagligi ve Hastaliklari Dergisi, vol.40, no.1, pp.29-36, 1997 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 1
  • Publication Date: 1997
  • Journal Name: Cocuk Sagligi ve Hastaliklari Dergisi
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.29-36
  • Bursa Uludag University Affiliated: Yes

Abstract

The aim of this study was to investigate the results of PPD-S (standard tuberculin) and PPD-B (bovine tuberculin), the correlation of PPD induration with BCG scar and the booster effect in children who were given BCG at the age of three months. Term, healthy intents with weights of 2500-4000 g were included in this study. In order to control for natural immunization or infection with any mycobacteria, all infants were given PPD-S and PPD-B before BCG vaccination. There was no significant difference between PPD-S and PPD-B results before and three months after vaccination. The mean induration size of PPD-S was found to be 1.4 mm higher than the mean of PPD-B six months after vaccination. Although statistically significant (p<0.001) a difference of 1.4 mm was thought to be impractical for clinical use. There was no difference between the mean PPD-S and PPD-B nine months after vaccination. A booster effect was found with both kinds of PPD. However this effect was found to be higher for PPD-S. There was no correlation between PPD-S or PPD-B induration and the size of the BCG scar. Therefore either PPD-S or PPD-B may be used for the investigation of the effect of BCG vaccination or exposure to an infection with any kind of mycobacterium.