Impact of pH on the activity of co-used antimicrobials against resistant Escherichia coli strains of animal origin

CENGİZ M., Hepbostanci G.

TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, vol.44, no.3, pp.747-751, 2020 (SCI-Expanded, Scopus, TRDizin) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.3906/vet-1912-67
  • Journal Name: TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.747-751
  • Bursa Uludag University Affiliated: Yes

Abstract

In this study, combination antimicrobial therapy, due to its higher potential against resistant bacteria, was evaluated for the inhibition of multidrug-resistant E. coli strains. The influence of pH as an environmental variable on the activity of antimicrobial combinations was evaluated by calculating the factional concentration indexes at pH values 5.0, 6.0, 7.3, and 8.0.