Fluvastatin Decreases Oxidative Stress in Kidney Transplant Patients


Yildiz A., Gullulu C. B. , Ocak N., Ersoy A., Sag S., Oruc A., ...More

TRANSPLANTATION PROCEEDINGS, vol.47, no.10, pp.2870-2874, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 10
  • Publication Date: 2015
  • Doi Number: 10.1016/j.transproceed.2015.10.027
  • Journal Name: TRANSPLANTATION PROCEEDINGS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2870-2874
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective. Oxidative stress has been suggested to have a pivotal role in the development of cardiovascular disease in kidney transplant patients (KTPs). The effects of fluvastatin on oxidative status in KTPs have not been well evaluated. The aim of the present study was to evaluate the effects of fluvastatin on oxidative status by investigating erythrocyte superoxide dismutase (SOD), erythrocyte glutathione peroxidase (GPx), serum paraoxonase (PON1), and serum arylesterase (ARE), along with lipid peroxidation products, serum malonldialdehyde, and apolipoprotein B malondialdehyde (ApoB MDA).