Delayed diagnosis of a neuroBehcet patient with only brainstem and cerebellar atrophy: Literature review

Taskapilioglu O., Seferoglu M., AKKAYA C., HAKYEMEZ B., Yusufoglu C., Basak A. N., ...Daha Fazla

JOURNAL OF THE NEUROLOGICAL SCIENCES, cilt.277, ss.160-163, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 277
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.jns.2008.10.003
  • Dergi Adı: JOURNAL OF THE NEUROLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.160-163
  • Anahtar Kelimeler: NeuroBehcet's Disease, Central nervous system, Cerebellar and brainstem atrophy, Psychiatric symptoms, Magnetic resonance imaging, NEURO-BEHCET-DISEASE, HEADACHE, ATAXIA
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

We report a 34-year-old male neuroBehcet's Disease (NBD) patient with atypical magnetic resonance imaging (MRI) findings, whose behavioral problems were followed by progressive neurological symptoms. The patient was hospitalized due to forgetfulness, irritability, behavioral dyscontrol and a choking sensation. T2-weighted MRI showed prominent atrophy of cerebellar hemispheres, the cerebellar peduncle, the midbrain and the pons. He was diagnosed with NBD after an evaluation of his medical history together with neuropsychiatric and laboratory findings. There are few reports of NBD with only brainstem and cerebellar atrophy. We discuss our patient in the context of the four previously reported cases. In NBD without evident mucocutaneo-ocular symptoms, neurologists should always consider the medical and family history. Early diagnosis of NBD helps to initiate appropriate treatment, thereby modulating the course of the disease and preventing complications. (C) 2008 Elsevier B.V. All rights reserved.