A synthesis of (S)-alpha-(fluorodiphenylmethyl)alkylamines by HF-pyridine treatment of 4-alkyl-5,5-diphenyl-oxazolidinones

O'Hagan D., Royer F., TAVASLI M.

TETRAHEDRON-ASYMMETRY, vol.11, no.9, pp.2033-2036, 2000 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 9
  • Publication Date: 2000
  • Doi Number: 10.1016/s0957-4166(00)00142-7
  • Journal Name: TETRAHEDRON-ASYMMETRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2033-2036
  • Bursa Uludag University Affiliated: No

Abstract

Treatment of enantiomerically pure (S)-4-alkyl-5,5-diphenyl-oxazolidinones, themselves derived from appropriate amino acids, with HF-pyridine (Olah's reagent) generated a range of (S)-alpha-(fluoro-diphenylmerhyl)alkylamines. These compounds represent a novel range of fluorinated chiral amines. (C) 2000 Elsevier Science Ltd. All rights reserved.