Anesthesia with remifentanil combined with sevoflurane, desflurane or propofol: Comparison of recovery characteristics, complications and the cost of anesthetics Remifentanil ile kombine edilen sevofluran, desfluran veya propofol anestezisi: Derlenme özelliklerinin, komplikasyonlarin ve anestezik i̇laç maliyetlerinin karşilaştirilmasi


Tüfek A., BİLGİN H., Özean B., TÜRKER Y. G.

Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, vol.34, no.2, pp.103-110, 2006 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 2
  • Publication Date: 2006
  • Journal Name: Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.103-110
  • Keywords: Cost, Desflurane, Propofol, Recovery, Remifentanil, Sevoflurane

Abstract

Aim: In this study, we purposed to compare desflurane, sevoflurane, and propofol with respect to their effect on early recovery characteristics, anesthesia-related complications and the cost of anesthetics when combined with remifentanil for the maintenance of anesthesia. Materials and Methods: Sixty women undergoing abdominal hysterectomy were randomly assigned to one of the three treatment groups. After standardized induction of anesthesia and tracheal intubation sequence, anesthesia was maintained with either sevoflurane 0.5-2% (Group S), desfurane 2-6% (Group D), or propofol 50-150 μg kg-1 min-1 (Group P) in combination with remifentanil 0.125-0.25 μgr kg-1 min-1 and nitrous oxide 60% in oxygen. Early recovery times (times to spontaneous breathing, eye opening, extubation, orientation and transfer to postanesthesia care unit), postanesthesia recovery scores (Modified Aldrete Scores) and anesthesia-related complications were evaluated during the immediate postoperative period. Results: Overall early recovery times were significantly shorter in Group D compared with the other two treatment groups (p value ranges: 0.05-0.001). However, there were no significant differences between Group S and Group P regarding these recovery parameters. Total cost of the anesthetics was found to be similar in the three groups. Conclusion: Abdominal hysterectomy patients anesthetized with desflurane had shorter postanesthesia recovery times than that of sevoflurane and propofol. Further, anesthesia with desflurane may increase turnover of operating room and productivity due to its early recovery properties.