Alterations of serum cytokine levels and their relation with inflammatory markers in candidemia


Akin H., Akalin H. , BUDAK F. , ENER B. , OCAKOĞLU G. , Gurcuoglu E., ...More

MEDICAL MYCOLOGY, vol.53, no.3, pp.258-268, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1093/mmy/myu084
  • Title of Journal : MEDICAL MYCOLOGY
  • Page Numbers: pp.258-268
  • Keywords: candidemia, IL-17, IL-23, PCT, sepsis, C-REACTIVE PROTEIN, CRITICALLY-ILL PATIENTS, NECROSIS-FACTOR-ALPHA, INTENSIVE-CARE-UNIT, INVASIVE CANDIDIASIS, INTERNATIONAL MULTICENTER, PROCALCITONIN PCT, RESPONSE SYNDROME, EARLY-DIAGNOSIS, SEVERE SEPSIS

Abstract

The roles of CRP, PCT, serum amyloid A (SAA), and cytokines in the diagnosis of fungal infections have not yet been clearly demonstrated. This study aims to measure the serum levels of interleukin (IL)-23, IL-17, IL-1 beta, tumor necrosis factor (TNF)-alpha, IL-10, transforming growth factor (TGF)-beta, C-reactive protein (CRP), procalcitonin (PCT), and serum amyloid A (SAA) in cases of candidemia and to compare them with those observed in cases of bacteremia.