Alterations of serum cytokine levels and their relation with inflammatory markers in candidemia


Akin H., Akalin H., BUDAK F., ENER B., OCAKOĞLU G., Gurcuoglu E., ...More

MEDICAL MYCOLOGY, vol.53, no.3, pp.258-268, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1093/mmy/myu084
  • Journal Name: MEDICAL MYCOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.258-268
  • Keywords: candidemia, IL-17, IL-23, PCT, sepsis, C-REACTIVE PROTEIN, CRITICALLY-ILL PATIENTS, NECROSIS-FACTOR-ALPHA, INTENSIVE-CARE-UNIT, INVASIVE CANDIDIASIS, INTERNATIONAL MULTICENTER, PROCALCITONIN PCT, RESPONSE SYNDROME, EARLY-DIAGNOSIS, SEVERE SEPSIS

Abstract

The roles of CRP, PCT, serum amyloid A (SAA), and cytokines in the diagnosis of fungal infections have not yet been clearly demonstrated. This study aims to measure the serum levels of interleukin (IL)-23, IL-17, IL-1 beta, tumor necrosis factor (TNF)-alpha, IL-10, transforming growth factor (TGF)-beta, C-reactive protein (CRP), procalcitonin (PCT), and serum amyloid A (SAA) in cases of candidemia and to compare them with those observed in cases of bacteremia.