Alterations of serum cytokine levels and their relation with inflammatory markers in candidemia

Akin, Hicran; Akalin, EMİN; Budak, FERAH; Ener, BEYZA; Ocakoğlu, GÖKHAN; Gurcuoglu, Emel; Goral, Guher; Oral, HALUK

doi:10.1093/mmy/myu084

Alterations of serum cytokine levels and their relation with inflammatory markers in candidemia

Akin H., Akalin H., Budak F., Ener B., Ocakoğlu G., Gurcuoglu E., ...Daha Fazla

MEDICAL MYCOLOGY, cilt.53, sa.3, ss.258-268, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 53 Sayı: 3
Basım Tarihi: 2015
Doi Numarası: 10.1093/mmy/myu084
Dergi Adı: MEDICAL MYCOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.258-268
Anahtar Kelimeler: candidemia, IL-17, IL-23, PCT, sepsis, C-REACTIVE PROTEIN, CRITICALLY-ILL PATIENTS, NECROSIS-FACTOR-ALPHA, INTENSIVE-CARE-UNIT, INVASIVE CANDIDIASIS, INTERNATIONAL MULTICENTER, PROCALCITONIN PCT, RESPONSE SYNDROME, EARLY-DIAGNOSIS, SEVERE SEPSIS
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

The roles of CRP, PCT, serum amyloid A (SAA), and cytokines in the diagnosis of fungal infections have not yet been clearly demonstrated. This study aims to measure the serum levels of interleukin (IL)-23, IL-17, IL-1 beta, tumor necrosis factor (TNF)-alpha, IL-10, transforming growth factor (TGF)-beta, C-reactive protein (CRP), procalcitonin (PCT), and serum amyloid A (SAA) in cases of candidemia and to compare them with those observed in cases of bacteremia.