Use of Colistin in a Neonatal Intensive Care Unit: A Cohort Study of 65 Patients


Cagan E., Bas E. K. , Asker H. S.

MEDICAL SCIENCE MONITOR, vol.23, pp.548-554, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23
  • Publication Date: 2017
  • Doi Number: 10.12659/msm.898213
  • Title of Journal : MEDICAL SCIENCE MONITOR
  • Page Numbers: pp.548-554

Abstract

Background: The emergence of infections related to multidrug-resistant Gram-negative bacilli (MDR-GNB) reintroduced the use of colistin, an antibiotic that was previously abandoned due to adverse effects. However, because of its limited use in neonatal intensive care units, there is very little data about the effectiveness and safety of colistin in children and newborns. In this study, which will be the largest case study in the literature, we aimed to evaluate the effectiveness and safety of colistin in full-term and preterm newborns.