Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Marker of Diabetic Nephropathy in Type 1 Diabetic Patients

Sisman, Pinar; ÖZ GÜL, ÖZEN; Dirican, MELEHAT; Bal, Ahmet; CANDER, SONER; ERTÜRK, ERDİNÇ

doi:10.7754/clin.lab.2019.190326

Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Marker of Diabetic Nephropathy in Type 1 Diabetic Patients

Sisman P., ÖZ GÜL Ö., Dirican M., Bal A. S., CANDER S., ERTÜRK E.

CLINICAL LABORATORY, cilt.66, sa.1-2, ss.9-16, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 66 Sayı: 1-2
Basım Tarihi: 2020
Doi Numarası: 10.7754/clin.lab.2019.190326
Dergi Adı: CLINICAL LABORATORY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
Sayfa Sayıları: ss.9-16
Anahtar Kelimeler: neutrophil gelatinase-associated lipocalin (NGAL), type 1 diabetes, diabetic nephropathy, KIDNEY INJURY MOLECULE-1, TUBULAR MARKERS, BIOMARKERS, DISEASE, PATHOPHYSIOLOGY, PROTEINURIA, PROGRESSION, DIAGNOSIS, DAMAGE
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background: Glomerular and tubulointerstitial damage plays a role in renal function failure in diabetic patients. While both serum and urine levels of neutrophil gelatinase-associated lipocalin (NGAL) show significantly increased levels in acute renal pathologies, the NGAL increase in active phase indicates a reversible condition in chronic cases.