Dynamic Contrast-Enhanced T1-Weighted Perfusion Magnetic Resonance Imaging Identifies Glioblastoma Immunohistochemical Biomarkers via Tumoral and Peritumoral Approach: A Pilot Study

Ozturk, Kerem; Soylu, Esra; TOLUNAY, ŞAHSİNE; NARTER, SELİN; HAKYEMEZ, BAHATTİN

doi:10.1016/j.wneu.2019.04.089

Dynamic Contrast-Enhanced T1-Weighted Perfusion Magnetic Resonance Imaging Identifies Glioblastoma Immunohistochemical Biomarkers via Tumoral and Peritumoral Approach: A Pilot Study

Ozturk K., Soylu E., TOLUNAY Ş., NARTER S., HAKYEMEZ B.

WORLD NEUROSURGERY, cilt.128, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 128
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.wneu.2019.04.089
Dergi Adı: WORLD NEUROSURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: Dynamic contrast-enhanced T1-weighted perfusion MR imaging (DCE-pMRI), Epidermal growth factor receptor (EGFR), Glioblastoma (GB), Isocitrate dehydrogenase 1 (IDH1), Oligodendrocyte transcription factor 2 (OLIG2), MICROVASCULAR PERMEABILITY, GENOMIC BIOMARKERS, HISTOGRAM ANALYSIS, MUTATION STATUS, MR, GLIOMA, PARAMETERS, DIFFERENTIATION, LYMPHOMA, SURVIVAL
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

OBJECTIVE: We aimed to evaluate the usefulness of dynamic contrast-enhanced T1-weighted perfusion magnetic resonance imaging (DCE-pMRI) to predict certain immunohistochemical (IHC) biomarkers of glioblastoma (GB) in this pilot study.