Association of vitamin D receptor gene Taq I polymorphism with recurrent urolithiasis in children
INTERNATIONAL JOURNAL OF UROLOGY, vol.14, no.12, pp.1060-1062, 2007 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 12
- Publication Date: 2007
- Doi Number: 10.1111/j.1442-2042.2007.01899.x
- Journal Name: INTERNATIONAL JOURNAL OF UROLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1060-1062
- Bursa Uludag University Affiliated: No
Abstract
Objective: Urolithiasis has a strong familial component. However, to date, no specific genetic abnormality has been identified. It has been reported that allelic variation in the vitamin D receptor ( VDR) gene may affect calcium absorption and excretion. Urolithiasis is a multifactorial disease in which both genetic and environmental factors have an effect on onset and severity of disease. In the present study, the role of Taq I polymorphism of vitamin D receptor gene in urolithiasis was studied.