Arterial dysfunction in early autosomal dominant polycystic kidney disease independent of fibroblast growth factor 23.


Yildiz A. , Gul C. B. , Ersoy A. , Asiltas B., Ermurat S., Dogan S., ...More

Iranian journal of kidney diseases, vol.8, pp.443-9, 2014 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8
  • Publication Date: 2014
  • Title of Journal : Iranian journal of kidney diseases
  • Page Numbers: pp.443-9
  • Keywords: arterial stiffness, autosomal dominant polycystic kidney disease, fibroblast growth factor 23, STAGE RENAL-DISEASE, ENDOTHELIAL DYSFUNCTION, NORMOTENSIVE PATIENTS, MORTALITY, KLOTHO, INFLAMMATION, RESISTANCE, MOUSE, HEART

Abstract

Introduction. Recent studies report reduced vascular compliance and elevated levels of fibroblast growth factor 23 (FGF23) in patients with autosomal dominant polycystic kidney disease (ADPKD) and preserved kidney function. In the present study, we investigated the relationship between vascular compliance and FGF23 in patients in early phases of ADPKD.