Neuroprotective effects of melatonin administered alone or in combination with topiramate in neonatal hypoxic-ischemic rat model
RESTORATIVE NEUROLOGY AND NEUROSCIENCE, cilt.30, sa.5, ss.435-444, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 5
- Basım Tarihi: 2012
- Doi Numarası: 10.3233/rnn-2012-120217
- Dergi Adı: RESTORATIVE NEUROLOGY AND NEUROSCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.435-444
- Anahtar Kelimeler: Combination therapy, hypoxia-ischemia, melatonin, neuroprotection, topiramate, BRAIN-DAMAGE, PROTECTIVE ROLE, CELL-DEATH, NEWBORN, INJURY, REDUCTION, INFANT
- Bursa Uludağ Üniversitesi Adresli: Evet
Özet
Purpose: The objective of this study was to compare the effects of two neuroprotective agents; melatonin, a free radical scavenger and topiramate, AMPA/kainate receptor antagonist, administered alone or in combination in neonatal hypoxic-ischemic model.