HIGH PREVALENCE OF CLASS I AND CLASS II INTEGRONS IN UROPATHOGENIC E. COLI STRAINS (UPECs) AND THEIR RELATIONSHIP WITH ANTIBIOTIC RESISTANCE, PHYLOGENY AND VIRULENCE

GÜMÜŞ, DEFNE; Yuksek, Fatma; Camadan, Firdevs; Oral, Merve; Macunluoglu, Asli; Kucuker, Mine

doi:10.26650/iuitfd.2022.984487

HIGH PREVALENCE OF CLASS I AND CLASS II INTEGRONS IN UROPATHOGENIC E. COLI STRAINS (UPECs) AND THEIR RELATIONSHIP WITH ANTIBIOTIC RESISTANCE, PHYLOGENY AND VIRULENCE

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GÜMÜŞ D., Yuksek F. K., Camadan F. D., Oral M., Macunluoglu A. C., Kucuker M. A.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, 2022 (ESCI)

Publication Type: Article / Article
Publication Date: 2022
Doi Number: 10.26650/iuitfd.2022.984487
Journal Name: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Keywords: Uropathogenic E. coli, phylogroups, integrons, virulence factors, antibiotic resistance, URINARY-TRACT-INFECTIONS, ESCHERICHIA-COLI, GENE CASSETTES, ANTIMICROBIAL RESISTANCE
Bursa Uludag University Affiliated: Yes

Abstract

Objective: Integrons, which are highly effective in capturing, integrating and expressing gene cassettes, play an important role in the dissemination of multiple antibiotic resistances. This study investigated the correlations of integrons in uropathogenic E. coli (UPEC) with antibiotic resistance, virulence and phylogeny and also the relationships of phylogroups with virulence and antibiotic resistance.