Efficacy of losartan in patients with primary focal segmental glomerulosclerosis resistant to immunosuppressive treatment

Usta M., Ersoy A., Dilek K., Ozdemir B., Yavuz M., Gullulu M., ...Daha Fazla

JOURNAL OF INTERNAL MEDICINE, cilt.253, sa.3, ss.329-334, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 253 Sayı: 3
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1046/j.1365-2796.2003.01071.x
  • Dergi Adı: JOURNAL OF INTERNAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.329-334
  • Anahtar Kelimeler: angiotensin receptor blockade, focal seg- mental glomerulosclerosis, losartan, proteinuria, treatment resistant, CONVERTING-ENZYME-INHIBITION, RENIN-ANGIOTENSIN SYSTEM, RENAL-FUNCTION, GLOMERULAR SCLEROSIS, NEPHROPATHY, PROTEINURIA, ABLATION, RAMIPRIL, DECLINE, THERAPY
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objectives. Angiotensin II may play an important role in the progression of renal disease. Currently, angiotensin converting enzyme (ACE) inhibitors and angiotensin II receptor antagonists are commonly used for renoprotection. To our knowledge, there is no study investigating this effect of angiotensin II receptor antagonists in patients with primary focal segmental glomerulosclerosis (FSGS) in the literature. The aim of this study was to evaluate the effects of losartan on proteinuria and renal function in patients with FSGS refractory to immunosuppressive treatment.