The efficacy of curcumin on PDGF expression and NF-kappa B pathway: TNBS-induced colitis

Altinel Y., Yalcin S., Ercan G., Yavuz E., Ercetin C., Gulcicek O. B., ...Daha Fazla

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, cilt.26, sa.5, ss.663-670, 2020 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.14744/tjtes.2019.45570
  • Dergi Adı: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.663-670
  • Anahtar Kelimeler: Anti-inflammatory, anti-oxidant, colitis, curcumin, NF-kappaB, SMOOTH-MUSCLE-CELLS, ULCERATIVE-COLITIS, MODEL, RATS, INNERVATION, THERAPY, EXTRACT, GROWTH
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

BACKGROUND: Curcumin is an antioxidant and anti-inflammatory molecule known to be a potent inhibitor of nuclear factor kappa B (NF-kappa B). In this study, we aimed to investigate the therapeutic effects of curcumin on colitis induced by a 2,4,6-trinitrobenzene sulfonic acid (TNBS).