The efficacy of curcumin on PDGF expression and NF-kappa B pathway: TNBS-induced colitis


Altinel Y., Yalcin S., Ercan G., Yavuz E., Ercetin C., Gulcicek O. B. , ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.26, no.5, pp.663-670, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.14744/tjtes.2019.45570
  • Title of Journal : ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Page Numbers: pp.663-670

Abstract

BACKGROUND: Curcumin is an antioxidant and anti-inflammatory molecule known to be a potent inhibitor of nuclear factor kappa B (NF-kappa B). In this study, we aimed to investigate the therapeutic effects of curcumin on colitis induced by a 2,4,6-trinitrobenzene sulfonic acid (TNBS).