P-wave and QT dispersion in hypertensive disorders of pregnancy

Dincgez Cakmak B., Dundar B., Ketenci Gencer F., Turker U., Kanat S.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, vol.32, no.24, pp.4051-4059, 2019 (SCI-Expanded) identifier identifier identifier


Aim: To compare P-wave and QT dispersion values in hypertensive disorders of pregnancy and controls and also in preeclampsia, chronic hypertension, and gestational hypertension separately. Material and methods: We included 140 hypertensive pregnants and 110 healthy age-matched pregnants in this study. The hypertensive pregnants were divided into three subgroups: preeclampsia (n = 43), chronic hypertension (n = 51), and gestational hypertension (n = 46). P-wave and QT dispersion values were compared between groups. Results: Hypertensive pregnants had higher P-wave (41.74 +/- 5.51 vs. 37.73 +/- 5.62, p < .001) and QTc dispersion (45.44 +/- 7.62 vs. 39.77 +/- 8.34, p < .001) values. In subgroup analysis, P-wave dispersion and QTc dispersion were different between preeclamptic, chronic hypertensive, and gestational hypertensive patients. Also, they were significantly higher in chronic hypertension as compared to gestational hypertension and they were higher in preeclampsia than in gestational hypertension. No difference was found according to these parameters between preeclampsia and chronic hypertension. In correlation analysis, both P-wave dispersion and QTc dispersion were positively correlated with systolic (r = 0.409, p < .001 and r = 0.306, p < .001) and diastolic blood pressure (r = 0.390, p < .001 and r = 0.287, p < .001) which are main clinical determinants of hypertensive disorders. Conclusion: In clinical practice, chronic hypertensive pregnants are generally followed up in their future life for cardiovascular disorders. Also, we recommend that we must inform and follow preeclamptic patients for future cardiovascular diseases.