Spermatogonial stem cell sensitivity to capsaicin: An in vitro study

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Atıf İçin Kopyala

Mizrak S. C., Gadella B. M., Erdost H., Ozer A., Van Pelt A. M. M., Van Dissel-Emiliani F. M. F.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, cilt.6, 2008 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 6
• Basım Tarihi: 2008
• Doi Numarası: 10.1186/1477-7827-6-52
• Dergi Adı: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background: Conflicting reports have been published on the sensitivity of spermatogenesis to capsaicin (CAP), the pungent ingredient of hot chili peppers. Here, the effect of CAP on germ cell survival was investigated by using two testis germ cell lines as a model. As CAP is a potent agonist of the transient receptor potential vanilloid receptor 1 (TRPV1) and no information was available of its expression in germ cells, we also studied the presence of TRPV1 in the cultured cells and in germ cells in situ.