In the present work, the small size effects on stability properties of perforated microbeams under various types of deformable boundary conditions are studied considering the Fourier sine series solution procedure and a mathematical procedure known as Stokes’ transformation for the first time. The main benefit of the present method is that, in addition to considering both the gradient elasticity and the size effects, the kinematic boundary conditions are modeled by two elastic springs as deformable boundary conditions. The deformable boundary conditions and corresponding stability equation are described using the classical principle which are then used to construct a linear system of equations. Afterward, an eigenvalue problem is adopted to obtain critical buckling loads. The correctness and accuracy of the present model are demonstrated by comparing results with those available from other works in the literature. Moreover, a numerical problem is solved and presented in detail to show the influences of the perforation properties, geometrical, and the variation of small-scale parameters and foundation parameters on the stability behavior of the microbeams. In addition, according to the best knowledge of the authors, there is no study in the literature that examines the buckling behavior of perforated microbeams on elastic foundation with the gradient elasticity theory.