Relationship of Serum Levels of Anti-Desmoglein Antibodies and Direct Immunofluorescence Findings with Clinical Activity of Pemphigus

Yilmaz, Mediha; BÜLBÜL BAŞKAN, EMEL; BUDAK, FERAH; SARICAOĞLU, HAYRİYE; Tunali, Sukran

doi:10.4274/turkderm.45.18

Relationship of Serum Levels of Anti-Desmoglein Antibodies and Direct Immunofluorescence Findings with Clinical Activity of Pemphigus

Yilmaz M., BÜLBÜL BAŞKAN E., BUDAK F., SARICAOĞLU H., Tunali S.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, cilt.45, sa.2, ss.22-27, 2011 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 45 Sayı: 2
Basım Tarihi: 2011
Doi Numarası: 10.4274/turkderm.45.18
Dergi Adı: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.22-27
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background and Design: Pemphigus is an autoimmune disease that results in blistering of the skin and mucous membranes. In this study, we investigated the relationship between disease activity and remission with ELISA scores and direct immunofluorescence (IF) - two methods used for the detection of antibodies against desmoglein-1 (dsg-1) and desmoglein-3 (dsg-3) that are responsible for blister formation.