Relationship of Serum Levels of Anti-Desmoglein Antibodies and Direct Immunofluorescence Findings with Clinical Activity of Pemphigus


Yilmaz M., BÜLBÜL BAŞKAN E., BUDAK F., SARICAOĞLU H., Tunali S.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, vol.45, no.2, pp.22-27, 2011 (SCI-Expanded) identifier identifier

Abstract

Background and Design: Pemphigus is an autoimmune disease that results in blistering of the skin and mucous membranes. In this study, we investigated the relationship between disease activity and remission with ELISA scores and direct immunofluorescence (IF) - two methods used for the detection of antibodies against desmoglein-1 (dsg-1) and desmoglein-3 (dsg-3) that are responsible for blister formation.