Central choline suppresses plasma renin response to graded haemorrhage in rats


Isbil-Buyukcoskun N. , Ilcol Y. O. , CANSEV M. , Hamurtekin E., Ozluk K., Ulus I. H.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.35, no.9, pp.1023-1031, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 9
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1440-1681.2008.04978.x
  • Title of Journal : CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Page Numbers: pp.1023-1031

Abstract

1. Central administration of choline increases blood pressure in normotensive and hypotensive states by increasing plasma concentrations of vasopressin and catecholamines. We hypothesized that choline could also modulate the renin-angiotensin pathway, the third main pressor system in the body.