EURASIAN JOURNAL OF MEDICINE, vol.49, no.3, pp.188-192, 2017 (Journal Indexed in ESCI)
Article / Article
Title of Journal :
EURASIAN JOURNAL OF MEDICINE
Alagebrium, calcium channel blockage, carotid artery, nitric oxide, vasodilatation, GLYCATION END-PRODUCTS, CROSS-LINK BREAKER, RECEPTOR, ALT-711, AGES
Objective: In our study, the effects of glycosylated protein cross-link breaker, alagebrium was investigated on isolated rat carotid artery using myography. Alagebrium showed vasodilator effect on carotid artery rings; particularly, this effect was significantly increased in endothelium-intact rings.