Paricalcitol Protects Peritoneal Membrane Function in Encapsulating Peritoneal Sclerosis


Gul C. B. , YILDIZ A. , AYTAÇ VURUŞKAN B. , ÖZ GÜL Ö. , ORUÇ A. , Aktas N., ...More

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.25, no.3, pp.283-288, 2016 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.5262/tndt.2016.1003.12
  • Title of Journal : TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
  • Page Numbers: pp.283-288

Abstract

OBJECTIVE: The most lethal complication of peritoneal dialysis is encapsulating peritoneal sclerosis (EPS), which develops as a result of epithelio-mesenchymal transformation (EMT) and known fibrotic processes. Paricalcitol has previously been shown to inhibit both EMT and fibrosis. We investigated the effect of paricalcitol on EPS.