Roles of plant and fungal lectins in cancer diagnosis and treatment: a scoping review

Kasapoğlu T., Dere E.

International Journal of Science Technology and Design, sa.3, ss.28-55, 2022 (Hakemli Dergi)

Özet

Lectins are proteins that possess the carbohydrate-binding property that makes the lectins can bind and recognize carbohydrate moieties on cancer cells. Lectins trigger various cell death forms such as apoptosis, autophagy, and necrosis in various cancer cell lines. These abilities of lectins are making the lectins a potential and convenient tool for cancer treatment and diagnosis. According to carbohydrate specificities and affinities, sequence similarities, the number of carbohydrate-binding domains, etc., lectins are classified into many groups. Therefore, the different lectins in each other have distinct affinities in various cancer cell lines. The researches and reviews of the potential use in cancer treatment and diagnosis of plant and fungal lectins have been aimed to document in this review