Importance of novel sequence alterations in the FHIT gene on formation of breast cancer

ÇEÇENER G., Egeli Ü., TUNCA B., Tasdelen I., TOLUNAY Ş., Bilgel N.

TUMORI J, vol.93, no.6, pp.597-603, 2007 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 93 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1177/030089160709300614
  • Journal Name: TUMORI J
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.597-603


Aims and background: The character, role and impact of FHIT gene alterations, for which recent studies have shown that the gene has a role in the early stage of carcinogenesis in breast cancer, are still unclear. Thus, the current study evaluated FHIT gene mutations from breast tissue of women with malignant and benign breast disease and to elucidate the frequency and type of mutations in this gene.