in: Integrative Bioinformatics , Ming Chen,Ralf Hofestädt, Editor, Springer Nature, Berlin, pp.3-9, 2022
This chapter introduces the history of Integrative Bioinformatics. Particularly, it outlines major events in the field from Germany who took a leading role and from China who plays a rapid developing counterpart. The earliest bioinformatics database resources, projects and initiatives are mentioned. We are stepping into the biological big data era, which requires us to develop new methods, cutting-edge technologies to deal with the vast multi-scale and multi-dimensional data. Several directions that may lead to solve the bottleneck of Integrative Bioinformatics are discussed. As life-sciences become more data-driven, Integrative Bioinformatics aims to integrate various aspects together to comprehensively understand the mechanism of life, and make the outputs available for use in the industry.