© 2022 Elsevier LtdIn this study, a new approach is proposed based on drone-assisted smart data gathering for pandemic situations. Drones can play important roles in highly dynamic and dense disaster areas for the data gathering process. Under these conditions, if big data gathering is necessary, the network traffic can be lightened and balanced with smart techniques. For these reasons, the drones construct the aerial network and scan the frequency bands in their coverage area. Then the collected data on the related drone is processed in terms of importance and priority levels. The drones take on fog computing capabilities for the specific duties. So, the unnecessary data will not be transmitted to the related destinations and the most priority data will be transferred immediately to the related units. The proposed mechanism is developed and examined with various scenarios. The throughput, delay and energy consumption performance metrics are considered for performance evaluation.