BCG vaccination in patients with severe combined immunodeficiency: complications, risks, and vaccination policies.

Marciano B. E., Huang C., Joshi G., Rezaei N., Carvalho B. C., Allwood Z., ...Daha Fazla

The Journal of allergy and clinical immunology, cilt.133, sa.4, ss.1134-41, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 133 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.jaci.2014.02.028
  • Dergi Adı: The Journal of allergy and clinical immunology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1134-41
  • Anahtar Kelimeler: Primary immunodeficiency, severe combined immunodeficiency, vaccine, BCG, mycobacteria, newborn screening, hematopoietic stem cell transplant, immune reconstitution syndrome, BACILLUS-CALMETTE-GUERIN, CENTRAL-NERVOUS-SYSTEM, IMMUNOCOMPROMISED CHILDREN, TUBERCULOUS MENINGITIS, VACCINES
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background: Severe combined immunodeficiency (SCID) is a syndrome characterized by profound T-cell deficiency. BCG vaccine is contraindicated in patients with SCID. Because most countries encourage BCG vaccination at birth, a high percentage of patients with SCID are vaccinated before their immune defect is detected.