BCG vaccination in patients with severe combined immunodeficiency: complications, risks, and vaccination policies.
The Journal of allergy and clinical immunology, cilt.133, sa.4, ss.1134-41, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 133 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.1016/j.jaci.2014.02.028
- Dergi Adı: The Journal of allergy and clinical immunology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1134-41
- Anahtar Kelimeler: Primary immunodeficiency, severe combined immunodeficiency, vaccine, BCG, mycobacteria, newborn screening, hematopoietic stem cell transplant, immune reconstitution syndrome, BACILLUS-CALMETTE-GUERIN, CENTRAL-NERVOUS-SYSTEM, IMMUNOCOMPROMISED CHILDREN, TUBERCULOUS MENINGITIS, VACCINES
- Bursa Uludağ Üniversitesi Adresli: Evet
Özet
Background: Severe combined immunodeficiency (SCID) is a syndrome characterized by profound T-cell deficiency. BCG vaccine is contraindicated in patients with SCID. Because most countries encourage BCG vaccination at birth, a high percentage of patients with SCID are vaccinated before their immune defect is detected.