CARDIOVASCULAR EFFECTS OF CENTRALLY ADMINISTERED ARACHIDONIC ACID IN HAEMORRHAGE-INDUCED HYPOTENSIVE RATS: INVESTIGATION OF A PERIPHERAL MECHANISM


YALÇIN M. , AYDIN C.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.36, no.4, pp.447-453, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 4
  • Publication Date: 2009
  • Doi Number: 10.1111/j.1440-1681.2008.05087.x
  • Title of Journal : CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Page Numbers: pp.447-453
  • Keywords: alpha(1)-adrenoreceptor, angiotensin II receptors, arachidonic acid, catecholamine, hypotension, intracerebroventricular, renin activity, V-1 receptors, vasopressin, SYMPATHO-ADRENOMEDULLARY OUTFLOW, CENTRAL CHOLINERGIC SYSTEM, NORMOTENSIVE CONSCIOUS RATS, BLOOD-FLOW AUTOREGULATION, THROMBOXANE A2 ANALOG, NEWBORN PIGS, VASOPRESSIN SECRETION, CEREBRAL-CIRCULATION, INJECTED U-46619, ACTIVATION

Abstract

1. The aims of the present study were to determine the cardiovascular effects of arachidonic acid (AA) and to investigate the peripheral mechanisms mediating these effects in haemorrhage-induced hypotensive rats.