The synthesis of methoxy and keto mycolic acids containing methyl-trans-cyclopropanes


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Koza G. , Muzael M., Schubert-Rowles R. R. , Theunissen C., Al Dulayymi J. R. , Baird M. S.

TETRAHEDRON, vol.69, pp.6285-6296, 2013 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 69
  • Publication Date: 2013
  • Doi Number: 10.1016/j.tet.2013.04.134
  • Title of Journal : TETRAHEDRON
  • Page Numbers: pp.6285-6296
  • Keywords: Mycolic acids, Mycobacterium tuberculosis, trans-Cyclopropane, Methoxy-mycolic acid, Keto-mycolic acid, MYCOBACTERIUM-TUBERCULOSIS, SINGLE ENANTIOMERS, BIOSYNTHESIS, GENE, RECOGNITION, POINT

Abstract

The syntheses of a number of methoxy and keto-mycolic acids containing an alpha-methyl-trans-cyclopropane unit and with chain lengths identical to those reported in major homologues in natural samples are reported. (C) 2013 Elsevier Ltd. All rights reserved.