Transient splenial lesion of corpus callosum associated with antiepileptic drug: Conventional and diffusion-weighted magnetic resonance images

Hakyemez B. , Erdogan C., Yildirim N., Gokalp G., Parlak M.

ACTA RADIOLOGICA, vol.46, no.7, pp.734-736, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 7
  • Publication Date: 2005
  • Doi Number: 10.1080/02841850510021760
  • Title of Journal : ACTA RADIOLOGICA
  • Page Numbers: pp.734-736


Transient focal lesions of splenium of corpus callosum can be seen as a component of many central nervous system diseases, including antiepileptic drug toxicity. The conventional magnetic resonance (MR) findings of the disease are characteristic and include ovoid lesions with high signal intensity at T2-weighted MRI. Limited information exists about the diffusion-weighted MRI characteristics of these lesions vanishing completely after a period of time. We examined the conventional, FLAIR, and diffusion-weighted MR images of a patient complaining of depressive mood and anxiety disorder after 1 year receiving antiepileptic medication.